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Women Eligibility Requirements
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Must be of non-childbearing potential, pregnant or nursing
Body Mass Index (BMI)
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Participants should have a BMI of ≥30
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BMI is ≥ 27 kg/m2 AND diagnosed with one of the following weight-related co-morbidities:
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High Blood Pressure (hypertension)
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Type 2 diabetes (T2D)
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High Cholesterol (dyslipidemia)
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Medication Restrictions
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Weight loss medications
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Opioids
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Bupropion or Naltrexone containing products, such as Wellbutrin, Wellbutrin SR, Wellbutrin XL and Aplenzin
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Monoamine Oxidase Inhibitors (MOAIs)
Screening Procedures
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Vital signs
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Blood samples
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Urine pregnancy test and pregnancy prevention counseling (if applicable)
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Urine opioid test
Visit Details
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Visit 1 Screening
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Visit 2 Baseline/administer study drug
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Ongoing study visits every 3 months for 1 year
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End of study treatment visit within 7 days of stopping study drug
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Follow up phone call every 3 months for 1 years after last dose